To explore whether indirect co-culture with myeloma cells increases p16 or p21, commonly implicated in cellular senescence, NBM-MSCs were exposed to MM.1S and RPMI-8226 myeloma cells transwell co-culture for 48 h prior to adipogenic differentiation (21 days). capacity and gene manifestation profiles of preadipocytes and bone marrow MSCs. Our studies uncover that MM.1S cells cause … Continue reading To explore whether indirect co-culture with myeloma cells increases p16 or p21, commonly implicated in cellular senescence, NBM-MSCs were exposed to MM